Mutaflor® – with the unique probiotic active ingredient Escherichia coli strain Nissle 1917 for human gut health

Current registrations, clinical studies and casuistics demonstrate the broad range of ­Mutaflor applications. This reaches from chronic bowel diseases to the colonization prophylaxis of premature and full-term neonates all the way to the treatment of extraintestinal diseases.

The limitations of antibiotic therapy, which are becoming more and more visible by the development of multiresistant pathogenic microorganisms, heighten the interest in the probiotic medicinal product ­Mutaflor, containing E. coli strain Nissle 1917 as the active substance. New knowledge about the medicinal relevance of the microbiome to human health have been added.

Yomogi® and Yomogi® 250 mg – with S. boulardii against acute diarrhea and travellers’ diarrhea

Saccharomyces boulardii, or S. boulardii for short, is the medical synonym for Saccharomyces cerevisiae HANSEN CBS 5926.

The antimicrobial effect of S. ­boulardii in the intestine is based, amongst other things, on an antagonistic effect towards pathogenic bacteria and yeasts which are ‘undesired’ in the intestines of human beings. Mycocins are made partially responsible for this effect, which are excreted from S. ­boulardii and have a growthinhibiting effect on these harmful microorganisms.

Discovery of the yeast Saccharomyces ­boulardii goes back to the French microbiologist Henri ­Boulard. In the twenties of the last century in Indochina, he observed that the local inhabitants used an infusion beverage obtained from tropical fruits (including lychees) for the treatment of diarrhea, and isolated the yeast from the skin of these fruits.

Paidoflor® – Lactobacillus acidophilus as a supplementation to support a variety of intestinal functions

Lactobacillus acidophilus (L. acidophilus) is one of the most important “friendly bacteria” in the human intestine. As a probiotic, or "good" bacteria, it is part of the normal gut defense flora.

The species L. acidophilus was first isolated from infant feces and characterizes in the early 1900's by Ernst Moro, who named it first Bacillus acidophilus. In 1970 it was Hansen and Mocquot who adequately describe this strain for the first time  and designed for it a neotype strain, Lactobacilli. Their taxonomic studies revealed that Lactobacillus belongs to the family Lactobacillae.

Paidoflor helps to restore balance and regularity of the digestive system, e.g. in cases of diarrhea and obstipation.

Download international package insert Mutaflor and Mutaflor Suspension
Download international package insert Yomogi
Download international package insert Yomogi 250 mg
Download international package insert Paidoflor